Question 1

Is 4chems.com GDPR compliant?

Accepted Answer

Yes — the entire 4chems.com platform is fully GDPR compliant. We implement strict data protection, access control, and transparency measures in accordance with the EU General Data Protection Regulation (Regulation (EU) 2016/679).

Question 2

What cloud provider or data center is being used?

Accepted Answer

4chems.com operates on a secure, EU-based cloud infrastructure designed for regulatory and scientific data workloads. Our Solution is provided through ISO 27001–certified European data centers with redundant availability zones to ensure high availbility and data resilience. To avoid compliance risks we do not use Hyperscalers like AWS, Microsoft Azure or Google Cloud.

Question 3

What version of CHESAR are you running and how often is it updated?

Accepted Answer

At 4chems.com, we run the latest officially released version of CHESAR, fully synchronized with the ECHA publication cycle. Our CHESAR environment is updated within a few days after each ECHA release, ensuring full compatibility with the current IUCLID data format and the most recent REACH Chemical Safety Assessment (CSA) requirements.

Question 4

Who owns the data hosted in your solution?

Accepted Answer

At 4chems.com, our customers always retain full ownership of their data. We act solely as a data processor under GDPR, while the customer remains the data controller. All information including IUCLID datasets, CHESAR assessments and QSAR models, belongs entirely to the customer. 4chems.com does not access, share, or use customer data for any purpose other than providing the contracted service. Upon request or contract termination, customers can export or permanently delete all their data. Backups and replicas are securely maintained only for availability and integrity, in compliance with GDPR and data retention policies.

Question 5

What version of IUCLID are you running and how often is it updated?

Accepted Answer

At 4chems.com, we always maintain the latest official release of IUCLID, aligned with the European Chemicals Agency (ECHA) schedule. Our IUCLID environment is currently running the latest production version published by ECHA (updated immediately after each official release). We typically update within a few days of every ECHA release, ensuring full compatibility with REACH, CLP, and OECD formats.

Question 6

Who handles system administration?

Accepted Answer

4chems.com manages all platform-level administration, ensuring the environment remains secure, up-to-date, and compliant. Customers do not have access to the underlying infrastructure.

Question 7

Can I migrate my existing self-hosted IUCLID to 4chems.com?

Accepted Answer

Yes — we provide full migration support for self-hosted IUCLID installations. Our team handles the complete migration process including data export from your on-premise instance, validation, and import into your managed cloud environment. We ensure zero data loss and minimal downtime. Whether you're running IUCLID on a local server or an internal network, we can migrate your datasets, user configurations, and submission history seamlessly.

Question 8

How does 4chems.com compare to ECHA's own IUCLID Cloud?

Accepted Answer

While ECHA provides a basic IUCLID Cloud service, 4chems.com offers a fully managed, enterprise-grade hosting solution with key advantages: dedicated environments with guaranteed performance (no shared resources), full CHESAR and QSAR Toolbox integration in the same platform, professional support with fast response times, automated backups and disaster recovery, and ISO 27001-certified EU data centers. We're ideal for organizations that need reliability, speed, and a complete regulatory toolkit — not just IUCLID alone.

Question 9

Do I need to install anything to use IUCLID, CHESAR, or QSAR Toolbox?

Accepted Answer

No — all tools are accessible directly through your web browser. There is no software to install, no Java dependencies to manage, and no server infrastructure to maintain. Simply log in and start working. This eliminates common pain points like version conflicts, update management, and local hardware requirements.

Question 10

Can I use IUCLID, CHESAR, and QSAR Toolbox together on 4chems.com?

Accepted Answer

Yes — one of the key advantages of 4chems.com is that IUCLID, CHESAR, QSAR Toolbox, and IIP are all available in a single integrated environment. Data flows seamlessly between tools: substance data from IUCLID is directly available in CHESAR for chemical safety assessments, and QSAR predictions can complement your dossier data. No manual file transfers or compatibility issues between tool versions.

Question 11

What database does 4chems run on?

Accepted Answer

PostgreSQL, on our own EU infrastructure. If you're coming from an Oracle-based setup, we migrate you to PostgreSQL with no Oracle licence needed on the target — and full ECHA support retained.

Question 12

How does the AI pre-validation work?

Accepted Answer

The assistant continuously checks your dossier for issues that IUCLID's built-in validation won't show you — the kind regulators usually find after submission. It flags them before you submit; you stay in control and decide what to fix.

Question 13

What is 4chems QSAR Navigator, and do I need it if I already have QSAR Toolbox hosting?

Accepted Answer

QSAR Navigator is an MCP (Model Context Protocol) gateway that lets an AI assistant operate your hosted QSAR Toolbox in plain regulatory language — defining a target substance, building a read-across category, filling the data gap, and drafting the QMRF, QPRF and CCR reports. It is an optional add-on to QSAR Toolbox cloud hosting, not a separate tool: the Toolbox does the science, QSAR Navigator lets an agent drive it. You keep working in the Toolbox as usual — the Navigator is there for when you want an assistant to run the workflow for you.

Question 14

Is my substance or dossier data sent to an external AI provider when I use QSAR Navigator?

Accepted Answer

QSAR Navigator itself runs on our ISO 27001-certified EU infrastructure and returns results to the AI assistant you connect. Which model or provider sees those results depends on the AI client you choose, so you control that boundary. The gateway sends only what is needed for the step being performed — it never bulk-exports your data — and every operation that touches your environment requires a token tied to your own tenant. 4chems acts solely as a data processor under GDPR and never uses your data to train models or for any purpose beyond providing the service.

Question 15

Does QSAR Navigator make regulatory decisions for me — is the output submission-ready and defensible?

Accepted Answer

No — the assessor stays in control. QSAR Navigator automates the mechanics (profiling analogues, gathering data, fitting the trend model, drafting reports) and produces the OECD deliverables — QMRF, QPRF and CCR — together with the RAAF category-consistency and Klimisch-style reliability evidence regulators expect. You review and approve every prediction before it becomes part of a dossier. The assistant accelerates the work; the toxicologist remains accountable for the conclusions.

Question 16

Which AI assistants does QSAR Navigator work with, and how do I connect?

Accepted Answer

Any Model Context Protocol (MCP) client — for example Claude Desktop or Claude Code — by adding the QSAR Navigator endpoint and your access token. Listing the available operations is anonymous, but every operation that touches your environment requires a per-tenant Bearer token issued by 4chems.

Question 17

Is QSAR Navigator available now, and how is it priced?

Accepted Answer

QSAR Navigator is available for early access to 4chems QSAR Toolbox hosting customers as an add-on. If you would like to try it or discuss pricing for your team, contact us and we will set you up.

Question 18

How is QSAR Navigator different from other QSAR Toolbox AI assistants?

Accepted Answer

Most AI assistants for the QSAR Toolbox are things you run yourself — you install and operate the Toolbox on your own Windows machine and connect a local script to it. QSAR Navigator is a fully managed, EU-hosted service: we run and keep the Toolbox current, access is authenticated per user, and you drive it from your own MCP-capable AI client (Claude, Copilot and others). It is designed to cover the full read-across and reporting workflow through to QMRF, QPRF and CCR — not just data lookups — and it runs under a GDPR data-processing agreement in ISO 27001-certified European data centres.

Question 19

Is there an MCP server for IUCLID?

Accepted Answer

Yes. 4chems runs a public Model Context Protocol (MCP) server at https://mcp.4chems.com/mcp for its hosted IUCLID, CHESAR and QSAR Toolbox platform. Connecting and listing tools is anonymous, and a set of tools (catalog, onboarding route, legal-entity types, account registration, sign-in and sending 4chems an inquiry) work without any token, so an AI assistant can answer first questions and reach us before you have an account. Tenant administration, consents, billing and invitations require a Bearer token issued by 4chems. Dossier data is not exposed on this endpoint: AI access to IUCLID 6 data runs through the 4chems AI Connector, and the QSAR Toolbox workflow through QSAR Navigator, both EU-hosted. Add it to Claude Code with 'claude mcp add --transport http 4chems https://mcp.4chems.com/mcp', or as a custom connector in Claude Desktop and claude.ai.

4chems.com - Verwaltetes IUCLID-, CHESAR- & QSAR-Toolbox-Hosting in der EU-Cloud.

Eine Plattform für Ihre gesamte Regulatory-Toolchain — jetzt mit KI, die Ihre Daten in Europa hält.

Was wir liefern

Die vier Dinge, die eine Einreichung zum Entgleisen bringen — und wie wir sie verhindern

Große Dossiers

Datenmigration

Versteckte Fehler vor der Einreichung

Reibungslose Einreichung bei Behörden

Häufig gestellte Fragen

Aktuelle regulatorische Einblicke

Gibt es einen MCP-Server für IUCLID? Ja. So verbinden Sie einen KI-Agenten

„Haben Sie das vorbereitet?“ Warum eine schnelle Demo trotzdem die Ausschreibung verlieren kann

Ihre IUCLID-5-Datei passt nicht in KKS

Erleben Sie Ihren eigenen Tool-Stack in der EU-Cloud — in einem 30-minütigen Walkthrough.